5-Amino-1MQ

10mg · Research Compound

A small-molecule NNMT inhibitor studied for cellular NAD+ elevation and adipocyte metabolism.

Form: Lyophilized

Storage: -20°C

$65 CAD

Research use only · lyophilized

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Research use only. You must be 18+ and a qualified researcher. Canada shipping only.

About this Compound

5-Amino-1MQ (5-amino-1-methylquinolinium) is a membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in adipose tissue that consumes the NAD+ precursor nicotinamide. By blocking NNMT, the compound is studied for its ability to raise cellular NAD+ and shift adipocyte energy metabolism.

Proposed Mechanism

Preclinical reports describe increased intracellular NAD+ and SAM, reduced lipogenesis in adipocytes, and decreased diet-induced fat mass in rodent models without reported changes in food intake. It is frequently studied alongside direct NAD+ precursors as a complementary pathway.

Specifications

Strength: 10mg per vial
Form: Lyophilized white powder
Reconstitution: Bacteriostatic water (sold separately)
Storage: Store lyophilized at -20°C. Reconstituted: 2-8°C, use within 30 days.

Research Disclaimer

This compound is supplied for in vitro research and laboratory use only. It is not a drug, food, cosmetic, or dietary supplement. It is not intended to diagnose, treat, cure, or prevent any disease, and is not for human or animal consumption.